Beschreibung

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Temazepam is a short-acting benzodiazepine, prescribed mainly for insomnia (difficulty falling or staying asleep) and occasionally used for pre-operative or procedural sedation . It enhances the calming neurotransmitter GABA in the brain to help you relax and sleep.

🛏️ Approved Uses & Onset

• Insomnia (short-term use): Helps you fall asleep faster and sleep more soundly.

• Pre-medication: Used before surgeries or dental procedures to reduce anxiety.

• Onset: Temazepam acts quickly—within 30 minutes—and its effects can last 7–8 hours, making it ideal for bedtime .

🔢 Dosage & Administration

• Typical adult dose: 7.5 to 30 mg taken at bedtime.

• Older adults or debilitated patients: Start at 7.5 mg at night .

• Duration: Recommended for short-term use only (≤2 weeks); extension beyond 4 weeks increases risk of dependence .

• Administration tip: Only take when you can get a full 7–8 hours of sleep—delayed awakening may occur otherwise.

⚠️ Side Effects & Risks

Common side effects

• Daytime drowsiness, dizziness, headache, dry mouth, muscle weakness, and dry mouth .

• Potential „hangover“ effect in the morning .

Serious side effects

• Complex sleep behaviors: sleepwalking, driving, eating or sex with no memory afterward .

• Severe allergic reactions, respiratory depression (especially if combined with alcohol/opioids), and paradoxical reactions like aggression or hallucinations.

Dependence & withdrawal

• Rapid development of tolerance and physical/psychological dependence—even with short-term use—can lead to withdrawal symptoms such as anxiety, insomnia, tremors, and seizures.

• Abrupt discontinuation can be dangerous; gradual tapering under medical supervision is essential en.wikipedia.org+2ginad.org+2verywellmind.com+2.

🚗 Interactions & Precautions

• Avoid alcohol and CNS depressants (like opioids): can cause severe sedation, respiratory depression, coma, or death .

• Contraindications: Patients with respiratory insufficiency, sleep apnea, myasthenia gravis, or severe liver/renal disease should generally avoid temazepam.

• Caution in elderly: Increased risk of falls, confusion, ataxia, and drug accumulation—and frailty increases vulnerability .

👨‍⚕️ Safe Usage Recommendations

1. Use only under physician supervision—no self-prescribing.

2. Start with lowest effective dose (e.g., 7.5 mg at bedtime).

3. Limit use to ≤2 weeks, with regular reassessments .

4. Do not mix with alcohol, opioids, or other sedatives.

5. Taper off gradually when stopping to avoid withdrawal .

6. Avoid operating vehicles or machinery while drowsy .

✅ Summary Table

🎯 Conclusion

Temazepam is an effective short-term treatment for insomnia and anxiety related to sleep. However, its high potential for tolerance, dependence, and serious side effects means it must be used cautiously—only under close medical supervision, with limited duration, low dosing, and careful monitoring.